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Sir Peter Hall Award for Research Excellence Finalist

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Environmental correlates of chronic obstructive pulmonary disease in 96779 participants from the UK Biobank: a cross-sectional, observational study

Dr Chinmoy Sarkar

(The University of Hong Kong, Faculty of Architecture, Department of Urban Planning and Design (DUPAD))

Co-authored by:

Dr Bing Zhang, Dr Michael Ni, Ms Sarika Kumari & Prof Chris Webster

(The University of Hong Kong)

Dr Sarah Bauermeister & Prof John Gallacher

(Oxford University)

Research Description

The role of environmental exposures in chronic obstructive pulmonary disease (COPD) remains inconclusive with very little evidence linking COPD with greenness and urbanicity. We used baseline data for UK Biobank participants to examine the associations between PM2·5, greenness, and urbanicity and COPD. Our study reported a 54·8% higher odds of COPD per 10 µg/m³ increment in PM2·5 exposure and 4·6% higher odds per interquartile range (IQR) increase in urbanicity. The effects were protective for residential greenness with 11·4% lower odds of COPD per IQR increment in greenness. The study highlights the value of planning and design in promoting respiratory health.

Full Entry Title

Chinmoy Sarkar, Bing Zhang, Michael Ni, Sarika Kumari, Sarah Bauermeister, John Gallacher, Chris Webster (2019) 'Environmental correlates of chronic obstructive pulmonary disease in 96 779 participants from the UK Biobank: a cross-sectional, observational study'. The Lancet Planetary Health, 3(11): e478-e490. https://doi.org/10.1016/S2542-5196(19)30214-1